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The junior associate editors of the Journal of Lipid Research have organized four virtual issues highlighting cutting-edge research published by the journal. 

Luciana Giono

Lipoprotein (a): Many strides made, yet there is a long road ahead

In this virtual issue, the JLR highlights early-career researchers pushing our understanding of lipoprotein (a) pathophysiology forward. According to Gissette Reyes-Soffer of the Columbia University Irving Medical Center, a better grasp of lipoprotein (a) is necessary to improve risk evaluations and targeted therapies for cardiovascular disease and diabetes.

The cover art depicts the Lp(a) particle following the steps of a walking path, increasing in size as the road goes into infinity.

Luciana Giono

Solving the enigma of the sphinx, one sphingolipid at a time

Recent studies have advanced our understanding of sphingolipids and their biologic roles in health and disease. This virtual issue, organized by Rotonya Carr of the University of Pennsylvania Perelman School of Medicine, also highlights both established and new investigators in the field who undoubtedly are the future of sphingolipid research.

The cover art features the structures of several sphingolipids being freed as the Sphinx unravels.

Luciana Giono

Lipids in transcription and chromatin biology

Ray Blind of the Vanderbilt University School of Medicine put together a virtual issue showcasing recent papers showing that lipids actively participate in epigenetic reprogramming, chromatin modifications and nucleosome structure, along with their more well-established roles in splicing, RNA export and transcriptional regulation.

The cover art is an abstract representation of nuclear lipids participating in the regulation of transcription and chromatin biology.